Dopamine transporter availability predicts ICDs
Reduced striatal dopamine transporter availability is already present in patients with Parkinson’s disease who go on to develop impulse control disorders, a study shows.
View ArticleVLSM provides more accurate prognosis of motor recovery from chronic stroke
Many studies have examined motor impairments using voxel-based lesion symptom mapping (VLSM), but few are reported regarding the corresponding relationship between cerebral cortex injury and lower limb...
View ArticleImaging biomarker proposed for Parkinson’s disease
Reduced off-medication connectivity in the basal ganglia network separates patients with early Parkinson’s disease from healthy controls with high accuracy, preliminary findings suggest.
View ArticleIn vivo dopaminergic imaging strongly correlates with brain pathology
Striatal dopamine transporter binding, assessed using single-photon emission computed tomography, is strongly correlated with substantia nigra cell counts assessed at postmortem, say the authors of a...
View ArticleSubcortical brain regions play key role in memorization process during sleep
According to researchers at the University of Montreal, the regions of the brain below the cortex play an important role as we train our bodies' movements and, critically, they interact more...
View ArticleBrain imaging could assist bipolar depression diagnosis
Researchers have identified structural brain differences that could help to distinguish patients with unipolar and bipolar depression.
View ArticleChanges in the brain may explain premature babies' higher risk of...
Disturbances in the early stages of brain growth, such as preterm birth - when many of the brain's structures have not yet fully developed - appears to affect the brain's neuro-circuitry, which may...
View ArticleSuccessful antipsychotic treatment may alter striatal connectivity
Connectivity within the striatum changes as psychotic symptoms improve in patients treated with second-generation antipsychotics, a study shows.
View ArticleAt-home test sniffs out prodromal Parkinson’s disease
An at-home olfactory test helps to identify people with an increased risk of having dopamine transporter imaging indicative of early Parkinson’s disease, show data from the Parkinson Associated Risk...
View ArticleInternational study identifies genetic factors that influence the size of...
An international study, which included researchers from NUI Galway, has identified significant genetic factors that influence the size of structures within the brain. It is hoped these new insights may...
View ArticleNew Penn Medicine study reveals how sleep deprivation increases intake of fat
Experts have warned for years that insufficient sleep can lead to weight gain. A new Penn Medicine study found that not only do we consume more food following a night of total sleep deprivation, but we...
View ArticleResting-state connectivity changes underpinning ICDs identified
The presence of impulse control disorders is associated with reduced resting-state connectivity between part of the associative striatum and both associative and limbic cortical regions in patients...
View ArticlePutaminal serotonergic innervation flags levodopa-induced dyskinesia risk
Increased serotonergic fibre innervation relative to dopaminergic fibre availability may be a potential marker of disease progression in Parkinson’s disease patients and a possible warning of...
View ArticleStudy shows food craving may be hard-wired into the brain of overweight patients
An international group of researchers have found that food craving activates different brain networks between obese and normal weight patients.
View ArticleResearchers examine use of MRI after birth to identify children at risk of...
School age children who are born prematurely are more likely to have low mathematical achievement, thought to be associated with reduced working memory and number skills, according to a new study...
View ArticleOlfactory function may inform Parkinson’s prognosis
Olfactory function is preserved in about a quarter of patients with Parkinson’s disease, and may be predictive of disease course, say researchers.
View ArticleSlow walking speed may herald Alzheimer’s disease
A slow walking speed in elderly people is associated with the presence of β-amyloid in their brains, research shows.
View ArticleAstrocytes implicated in preclinical AD
Astrocytes are activated in the brains of people with autosomal dominant Alzheimer’s disease long before symptoms appear and even before amyloidosis begins, a study shows.
View ArticlePitt experts lead gene therapy clinical trial in Parkinson's disease patients
Experts at the University of Pittsburgh School of Medicine are leading the second arm of a clinical trial using gene therapy to relieve the symptoms of tremor and mobility impairment in patients with...
View ArticlePatients with schizophrenia demonstrate specific leftward asymmetry for...
A Japanese research group found that patients with schizophrenia demonstrated a specific leftward volumetric asymmetry for the globus pallidus, one of the basal ganglia of the brain. The basal ganglia...
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