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Neural circuits respond to rapid dopamine surges

Researchers assess the pharmacodynamics of dopamine signaling, brain connectivity/activity, and self-documented 'high' following methylphenidate exposure.v

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Scientists develop noninvasive way to monitor gene expression dynamics in the...

Researchers introduced a non-invasive, sensitive method for monitoring gene expression in the brain using engineered reporters called released markers of activity, which can exit the brain into the...

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The impact of tackle football on adolescent brain structure and function

Researchers investigated adolescent footballer brain architecture and neurophysiological features.

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Study reveals pivotal insights into the progression of Parkinson's disease

Parkinson's disease, the second most common type of progressive dementia after Alzheimer's disease, affects nearly 1 million people in the U.S. and an estimated 10 million individuals worldwide.

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New research sheds light on how GLP-1 obesity drugs may change food cravings

GLP-1 analog treatments potentially alter food preferences and reduce obesity by decreasing appetite and food consumption, with further research needed for long-term weight maintenance using objective...

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Atypical brain connections linked to ADHD symptoms

Researchers at the National Institutes of Health (NIH) have discovered that symptoms of attention-deficit/hyperactivity disorder (ADHD) are tied to atypical interactions between the brain's frontal...

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COVID-19 survivors show lasting brain function alterations, fMRI study finds

The long-term impact of coronavirus disease 2019 (COVID-19) on brain function.

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Sleep and anesthesia hinder brain toxin clearance, study reveals

Researchers found that brain clearance is reduced during both sleep and anesthesia, contradicting the belief that these states enhance toxin removal.

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Study uncovers probable origin of stuttering in the brain

An international research group led by researchers from the University of Turku and Turku University Hospital in Finland has succeeded in identifying the probable origin of stuttering in the brain.

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Scientists locate the source of stuttering in the brain

An international research group led by researchers from the University of Turku and Turku University Hospital in Finland has succeeded in identifying the probable origin of stuttering in the brain.

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Novel insights into how exercise functions as an antidepressant

Researchers from University College London propose a novel framework linking reduced inflammation and boosted dopamine transmission through exercise to alleviate depressive symptoms.

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Research reveals only a few brain regions remain untouched by transition to...

Research shows pregnancy triggers neuroanatomical changes in the brain, with decreased cortical volume and increased white matter integrity over gestation.

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Lithium aspartate fails to improve long COVID symptoms, but higher doses may...

Lithium aspartate at 10-15 mg/d is ineffective for treating cognitive dysfunction and fatigue in long COVID, but higher doses may offer potential benefits based on a small follow-up study.

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Differential gene expression linked to alcohol use disorder, offering new...

Researchers identified key gene expression differences in addiction-relevant brain regions that provide new insights into alcohol use disorder and potential therapeutic targets.

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Researchers identify genetic links to brain volume and disorders

In one of the largest-ever studies of DNA and brain volume, researchers have identified 254 genetic variants that shape key structures in the "deep brain," including those that control memory, motor...

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Study connects brain volume variations with genetic risk factors for...

Unprecedented genome analysis reveals genetic links between brain structure and disorders like Parkinson's and ADHD, paving the way for innovative treatments.

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Parkinson's study reveals dopamine's unexpected link to tremor

Researchers from the Champalimaud Foundation shed light on the puzzling relationship between dopamine and rest tremor in Parkinson's disease, finding that preserved dopamine in certain brain regions...

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Human ability to process numbers traced to unexpected brain region

New research reveals the unique human ability to conceptualize numbers may be rooted deep within the brain.

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Early brain changes in Huntington’s disease detected two decades before symptoms

Subtle changes in the brain, detectable through advanced imaging, blood and spinal fluid analysis, happen approximately twenty years before a clinical motor diagnosis in people with Huntington's...

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Cell-by-cell analysis reveals brain changes in Tourette syndrome

In the first comprehensive, cell-by-cell analysis of brain tissue from individuals with Tourette syndrome, researchers have pinpointed exactly which cells are perturbed and how they malfunction,...

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